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Hildebrandt, John
One or more keywords matched the following items that are connected to Hildebrandt, John
Item TypeName
Academic Article Receptor docking sites for G-protein betagamma subunits. Implications for signal regulation.
Academic Article Heterogeneous processing of a G protein gamma subunit at a site critical for protein and membrane interactions.
Academic Article A major G protein alpha O isoform in bovine brain is deamidated at Asn346 and Asn347, residues involved in receptor coupling.
Academic Article A mutation in the putative Mg(2+)-binding site of Gs alpha prevents its activation by receptors.
Academic Article Structural characterization of intact G protein gamma subunits by mass spectrometry.
Academic Article Characterization of the major bovine brain Go alpha isoforms. Mapping the structural differences between the alpha subunit isoforms identifies a variable region of the protein involved in receptor interactions.
Academic Article The N54 mutant of Galphas has a conditional dominant negative phenotype which suppresses hormone-stimulated but not basal cAMP levels.
Academic Article The relationship of G(o)alpha subunit deamidation to the tissue distribution, nucleotide binding properties, and betagamma dimer interactions of G(o)alpha subunit isoforms.
Academic Article Gamma 2 subunit of G protein heterotrimer is an N-end rule ubiquitylation substrate.
Academic Article Identification of Gbetagamma binding sites in the third intracellular loop of the M(3)-muscarinic receptor and their role in receptor regulation.
Academic Article Genomic analysis of G protein gamma subunits in human and mouse - the relationship between conserved gene structure and G protein betagamma dimer formation.
Academic Article G Protein betagamma dimer formation: Gbeta and Ggamma differentially determine efficiency of in vitro dimer formation.
Academic Article Proteomic analysis of bovine brain G protein gamma subunit processing heterogeneity.
Academic Article Role of the chaperonin CCT/TRiC complex in G protein betagamma-dimer assembly.
Academic Article Distinct guanine nucleotide binding and release properties of the three Gi proteins.
Academic Article Differential regulation of G protein subunit expression in mouse oocytes, eggs, and early embryos.
Academic Article Analysis of signal transfer from receptor to Go/Gi in different membrane environments and receptor-independent activators of brain G protein.
Academic Article Separation and analysis of G protein gamma subunits.
Academic Article Synthesis and assembly of G protein ?? dimers: comparison of in vitro and in vivo studies.
Academic Article Two forms of the bovine brain Go that stimulate the inositol trisphosphate-mediated Cl- currents in Xenopus oocytes. Distinct guanine nucleotide binding properties.
Academic Article ADP-ribosylation of membrane components by pertussis and cholera toxin.
Academic Article Pertussis toxin alters the growth characteristics of Swiss 3T3 cells.
Academic Article Purification of Ns and Ni, the coupling proteins of hormone-sensitive adenylyl cyclases without intervention of activating regulatory ligands.
Academic Article Characterization by two-dimensional peptide mapping of the gamma subunits of Ns and Ni, the regulatory proteins of adenylyl cyclase, and of transducin, the guanine nucleotide-binding protein of rod outer segments of the eye.
Academic Article Updated protocols and comments on the purification without use of activating ligands of the coupling proteins Ns and Ni of the hormone sensitive adenylyl cyclase.
Academic Article Mechanisms in the vectorial receptor-adenylate cyclase signal transduction.
Academic Article Stimulation and inhibition of adenylyl cyclases mediated by distinct regulatory proteins.
Academic Article Pertussis toxin substrate, the putative Ni component of adenylyl cyclases, is an alpha beta heterodimer regulated by guanine nucleotide and magnesium.
Academic Article Effects of guanine nucleotides and Mg on human erythrocyte Ni and Ns, the regulatory components of adenylyl cyclase.
Academic Article Guanine nucleotide inhibition of cyc- S49 mouse lymphoma cell membrane adenylyl cyclase.
Academic Article Gi is involved in ethanol inhibition of L-type calcium channels in undifferentiated but not differentiated PC-12 cells.
Academic Article Factors determining specificity of signal transduction by G-protein-coupled receptors. Regulation of signal transfer from receptor to G-protein.
Academic Article Bovine brain GO isoforms have distinct gamma subunit compositions.
Academic Article Alterations in macrophage G proteins are associated with endotoxin tolerance.
Academic Article Characterization of a G-protein activator in the neuroblastoma-glioma cell hybrid NG108-15.
Academic Article Role of subunit diversity in signaling by heterotrimeric G proteins.
Academic Article A dominant negative Galphas mutant that prevents thyroid-stimulating hormone receptor activation of cAMP production and inositol 1,4,5-trisphosphate turnover: competition by different G proteins for activation by a common receptor.
Academic Article Complex haplotype structure of the human GNAS gene identifies a recombination hotspot centred on a single nucleotide polymorphism widely used in association studies.
Academic Article Hormone inhibition of adenylyl cyclase. Differences in the mechanisms for inhibition by hormones and G protein beta gamma.
Academic Article Sequence dependence and differential expression of Ggamma5 subunit isoforms of the heterotrimeric G proteins variably processed after prenylation in mammalian cells.
Academic Article G protein subunit interactions. Studies with biotinylated G protein subunits.
Academic Article Identification of a gamma subunit associated with the adenylyl cyclase regulatory proteins Ns and Ni.
Academic Article Interaction of the stimulatory and inhibitory regulatory proteins of the adenylyl cyclase system with the catalytic component of cyc-S49 cell membranes.
Academic Article Determination of the complete covalent structure of the gamma 2 subunit of bovine brain G proteins by mass spectrometry.
Academic Article Synthesis and use of biotinylated beta gamma complexes prepared from bovine brain G proteins.
Academic Article The effect of pertussis toxin on the growth of vascular smooth muscle cells stimulated by serum or platelet-derived growth factor.
Academic Article Gbeta subunit interacts with a peptide encoding region 956-982 of adenylyl cyclase 2. Cross-linking of the peptide to free Gbetagamma but not the heterotrimer.
Academic Article A surface on the G protein beta-subunit involved in interactions with adenylyl cyclases.
Concept GTP-Binding Protein alpha Subunits, Gi-Go
Concept Heterotrimeric GTP-Binding Proteins
Concept GTP-Binding Proteins
Concept GTP-Binding Protein gamma Subunits
Concept Guanosine Triphosphate
Concept GTP-Binding Protein alpha Subunits, Gs
Concept GTP-Binding Protein beta Subunits
Concept GTP Phosphohydrolases
Academic Article The N54-as Mutant Has Decreased Affinity for ?? and Suggests a Mechanism for Coupling Heterotrimeric G Protein Nucleotide Exchange with Subunit Dissociation.
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